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A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED FIELD TRIAL TO COMPARE THE EFFICACY OF ARTESUNATE AND PRAZIQUANTEL COMBINATION DRUG THERAPY

1. Background

Despite efforts to contain the disease, Schistosomiasis remains one of the severe debilitating illnesses in millions of people. Although it has a relatively low mortality rate, it has a high morbidity rate, causing schistosomiasis to often be a chronic illness that can cause liver and intestinal damage. The disease is mainly found in tropical countries in Africa, Caribbean, eastern South America, East Asia and in the Middle East. The World Health Organisation estimates that about 207 million people have the disease, 120 million symptomatic. There are five species of flatworms that cause schistosomiasis. Each type is prevalent in different parts of the world. S. haematobium, is the most virulent parasite in Africa and the Middle East.

6. Health and safety

All safety data should be listed highlighting clinical laboratory values outside the normal range. A COSHH form is attached for the use of formalin.

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